The synthesis of well-defined poly(vinylbenzyl chloride)-grafted nanoparticles via RAFT polymerization

• John Moraes,
• Kohji Ohno,
• Guillaume Gody,
• Thomas Maschmeyer and
• Sébastien Perrier

Beilstein J. Org. Chem. 2013, 9, 1226–1234, doi:10.3762/bjoc.9.139

• Sustainability, School of Chemistry, The University of Sydney, NSW 2006, Australia 10.3762/bjoc.9.139 Abstract We describe the use of one of the most advanced radical polymerization techniques, the reversible addition fragmentation chain transfer (RAFT) process, to produce highly functional core–shell particles

• , and we demonstrate that the exceptional control over their dimensions is achieved by careful tailoring the conditions of the radical polymerization. Keywords: core–shell particles; free radical; grafting; RAFT polymerization; silica; Introduction The versatility of organic free radical chemistry in

• . Nonetheless, since a predictable increase in Mn with conversion was demonstrated (a key requirement for the controlled synthesis of core–shell particles), we proceed to undertake the polymerization in the presence of silica-supported RAFT agents. In the preparation of the silica–polymer hybrid particles, our

Miniemulsion polymerization as a versatile tool for the synthesis of functionalized polymers

• Daniel Crespy and
• Katharina Landfester

Beilstein J. Org. Chem. 2010, 6, 1132–1148, doi:10.3762/bjoc.6.130

• –shell particles were prepared by miniemulsifying the styrene and a hydrophobic diisocyanate monomer followed by the addition of a diamine to the miniemulsion, and then the radical polymerization of styrene [112]. The presence of the polyurea shell was shown to prevent migration of encapsulated dye

• or polycondensation (Table 6). Since the surface generated by the miniemulsion droplets is extremely large, fast reactions are expected to occur in such systems. The formation of a thin film around the nanodroplets allow the creation of core–shell or capsular morphologies. Polystyrene–polyurea core

Hybrid biofunctional nanostructures as stimuli-responsive catalytic systems

• Gernot U. Marten,
• Thorsten Gelbrich and
• Annette M. Schmidt

Beilstein J. Org. Chem. 2010, 6, 922–931, doi:10.3762/bjoc.6.98

• water. By proper choice of the copolymer composition, the thermoflocculation temperature of the core–shell particles can be adjusted [34][35]. The biocompatibility of poly(ethylene glycol) derivates is helpful to obtain nanoparticles acceptable for use in in vitro biological systems. The direct

• were collected on a Mettler-Toledo DSC 822e at 5 K·min−1. TEM pictures were taken on a Hitachi H 600. Structures of comonomers employed in the synthesis of functional core–shell particles. TEM images of a) Fe3O4 nanoparticles electrostatically stabilized by citric acid; b) Fe3O4@P(M100) nanoparticles

• biomolecules [33]. In this respect it is of interest to note, that the cloud point temperature can be adjusted by copolymerization in a wide range, including temperatures acceptable for biomolecules and biological species (Figure 3a) [34]. Furthermore, it has been shown that thermoflocculation of core–shell